Genetic diseases, caused by an
abnormality by an abnormality in a person’s genome and even the person’s entire
genetic makeup, can range from minuscule to major and from a discrete mutation
in a single base in the DNA of a single gene to a gross chromosome abnormality.
Some of these genetic disorders are
inherited; from parents; while others are caused by acquired changes or
mutations in a pre-existing gene or group of genes. Not to mention the
mutations that can occur either randomly or due to some environmental exposure.
Know about Different
Types of Inheritance?
Genetic inheritances are divided into different categories –
mainly four categories that include:
Single Gene
It is caused by changes or mutations in the DNA sequence of
the single gene. Don’t surprise as there are more than 6000 known single-gene
disorders that may occur to 1 in 100 or sometimes not. Cystic fibrosis, sickle
cell anemia, Marfan syndrome, Huntington’s disease and Hemochromatosis are
different single gene disorders.
Multi-Factorial
This type of genetic disorder may take place due to
amalgamation of environmental factors and mutations in multiple genes. Heart
diseases, high blood pressure, Alzheimer’s diseases, arthritis, diabetes,
cancer and obesity are different types of potential diseases that may take
place due to this type of disorder. It also shows impacts in fingerprint
patterns, height, eye color and skin color.
Not to mention chromosome abnormalities that are the
important DNA and protein structure located in the nucleus of each cell. It is
important to know that chromosomes are the carriers of the genetic material,
abnormalities in chromosome number or structure that can result in disease.
Mitochondrial
Inheritance
This genetic disorder is due to mutations in the non-nuclear
DNA of mitochondria – small round organelles – involved in cellular respiration
or found in the cytoplasm of plant and animal cells. Each mitochondrion
contains 5 to 10 circular pieces of DNA. Not to mention egg cells, but not
sperm cells
that keep their mitochondria for the duration of
fertilization. Mitochondrial DNA is inherited from the female parent. Some of the common diseases include, but not
limited to:
·
Eye disease – called Leber’s hereditary optic
atrophy
·
Epilepsy that stands for Myoclonic Epilepsy with
ragged red fibers
·
A form of dementia, lactic acidosis and
stroke-like episodes
Before the genetic
diseases passes to next generation, it is important to get the genetic
tests done. For this, it is important to find a clinic where such genetic diseases
are done. ARThealthcare has been offering you such tests. You have to schedule
an appointment according to your choice.
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